CLEANING PROCEDURE FOR DISTILLED WATER STROAGE TANK

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CLEANING PROCEDURE FOR DISTILLED WATER STROAGE TANK


INTRODUCTION

The distilled water storage tank is used to collect and store pyrogen free distilled water obtained from the distillation still. It has to a temperature of 80 ºC to keep it pyrogen free since the distilled water is used for critical operation in sterile product manufacturing like rinsing of process equipment, vessels and utensils, rinsing of rubber stoppers etc.

Apart from being pyrogen free the distilled water should also be free from any particulate matter, hence, to endure this, the distilled water storage tank is periodically cleaned thoroughly and recored maintained.

PROCEDURE

Put the heater off and drain all the distilled water in the tank from bottom drain outlet.

Now disconnect the tank from multicolumn distillation still. Title the tank on the floor and dismantle the heating element, washers and temperature-sensing element.

Clean the tank from inside using clean sponge and filtered flowing DM water. Only if required, especially if any sticky particles are observed, use a nylon scrubber and 0.05% Benzalkonium Chloride solution (50%) for cleaning and then thoroughly rinse with flowing DM water.

Finally rinse three times with freshly collected pyrogen free distilled water, with completely draining the tank during each time of rinsing. Similarly, rinse he heating element, washer and the temperature sensor with only fresh pyrogen free distilled water thrice.

Fix the heating elements with washers and the temperature sensor to the tank and put the tank upright. Close the tank with the lid and connect it to the multicolumn distillation plant. Start the multicolumn distillation plant and collect about 50 liters of distilled water in the tank and then bottom drain the tank completely.

Now freshly collect the required amount of distilled water in the tank, and keeping the heater set at 80 ºC store the water for use, keeping the set heaters ‘ON’.

Record the date of cleaning and the name of the cleaning operator.

FREQUIENCY - MONTHLY